DALI

DALI removes cholesterol from blood


The DALI system (DALI = Direct Adsorption of Lipoproteins) was developed by Fresenius Medical Care researchers for patients with a hereditary disorder of the lipometabolism. This is the first process capable of removing LDL cholesterol from whole blood without separating it beforehand into blood cells and blood plasma. The DALI system is simple to operate and works safely and reliably.

People with a hereditary lipid metabolism disorder, known as familial hypercholesteremia, are often unable to reduce their high LDL cholesterol levels sufficiently with just diet and medications. These patients frequently suffer from arteriosclerosis at a young age and have a high risk of dying from coronary heart disease. During treatment, blood flows from a vein in the arm of the patient through a tube into the DALI adsorber, the heart of the system.

Lowering cholesterol level


The DALI adsorber consists of a plastic housing that is filled with tiny, porous beads. Like a large sponge, these beads extract LDL cholesterol from the blood. The cleansed blood is returned to the patient via a tube in the vein of the other arm.

A machine continuously monitors the blood flow outside the body by pumping the blood, controlling its velocity and preventing air from entering the blood flow. After about one or two hours of treatment, the LDL cholesterol level of the blood can decrease more than 60%. The procedure is well tolerated by patients who require treatment once a week on average.

top